Heat the oven to 350°F (175°C). Grease a 9x5 inch loaf pan and line it with parchment paper, leaving a little overhang on the long sides so you can lift the loaf out later.
In a large bowl, whisk together the flour, baking soda, baking powder, salt, cinnamon, nutmeg, and ginger.
In a second bowl, whisk the pumpkin puree, maple syrup, applesauce, oil, eggs, milk, and vanilla until smooth.
Pour the wet mixture into the dry mixture. Fold with a spatula just until no dry streaks remain. A few small lumps are fine.
Scrape the batter into the prepared pan and smooth the top. Sprinkle with pepitas if using.
Bake for 50 to 55 minutes, until a toothpick in the center comes out with a few moist crumbs. If the top browns too fast, cover loosely with foil after about 35 minutes.
Cool in the pan for 15 minutes, then lift the loaf out and let it cool on a wire rack for at least 30 minutes before slicing.